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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22957 | LY2606368 HCl (1234015-52-1 free base) | LY2606368 HCl | Others |
LY2606368 HCl is a selective ATP competitive inhibitor of checkpoint kinase 1 (IC50: 1.5nM in SW1990 cells). | |||
T4327 | Prexasertib dihydrochloride | LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368 | Apoptosis , Chk , S6 Kinase |
Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively. |